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Osteopontin Antikörper (AA 50-100)
SPP1
Reaktivität: Human, Maus, Ratte
WB, ELISA, IHC (p), IF
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5690268
Produktdetails anti-Osteopontin Antikörper
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Target
Alle Osteopontin (SPP1) Antikörper anzeigen
Osteopontin (SPP1)
(Secreted phosphoprotein 1 (SPP1))
Bindungsspezifität
Alle Epitope für Osteopontin Antikörper
AA 50-100
Reaktivität
Alle Reaktivitäten für Osteopontin Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für Osteopontin Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für Osteopontin Antikörper
Polyklonal
Konjugat
Alle Konjugate für Osteopontin Antikörper
Dieser Osteopontin Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Osteopontin Antikörper
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
Spezifität
SPP1 antibody is human, mouse and rat reactive. Multiple isoforms of SPP1 are known to exist.
Aufreinigung
SPP1 Antibody is affinity chromatography purified via peptide column.
Immunogen
SPP1 antibody was raised against an 18 amino acid peptide near the amino terminus of human SPP1. The immunogen is located within amino acids 50 - 100 of SPP1.
Isotyp
IgG
Top Product
Discover our top product SPP1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
SPP1 antibody can be used for detection of SPP1 by Western blot at 1 - 2 μ,g/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
SPP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
SPP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Details zu Osteopontin
(ausblenden)
Target
Osteopontin (SPP1)
(Secreted phosphoprotein 1 (SPP1))
Andere Bezeichnung
SPP1 (SPP1 Produkte )
Synonyme
BNSP antikoerper, BSPI antikoerper, ETA-1 antikoerper, OPN antikoerper, 2AR antikoerper, Apl-1 antikoerper, Bsp antikoerper, Eta antikoerper, OP antikoerper, Opn antikoerper, Opnl antikoerper, Ric antikoerper, Spp-1 antikoerper, OSP antikoerper, zgc:111821 antikoerper, secreted phosphoprotein 1 antikoerper, SPP1 antikoerper, Spp1 antikoerper, spp1 antikoerper
Hintergrund
SPP1 Antibody: The secreted protein 1 (SPP1), also known as osteopontin, is a major noncollagenous protein of bone, but is also found in the extracellular matrix of other mineralized tissues and in bodily fluids. In bone, SPP1 is produced by osteoblasts, osteocytes, macrophages, and osteoclasts (1,2). SPP1 binds to cells through integrin and non-integrin receptors, as well as the adhesion receptor CD44 in an RGD-independent manner, enabling SPP1 to induce a number of functional effects including macrophage chemotaxis, cytoprotection, and regulation of T helper type 1 cells (2). SPP1 can regulate biomineralization by inhibiting the formation of hydroxyapatite (3) and the growth of calcium oxalate crystals (4).
Molekulargewicht
Predicted: 36 kDa Observed: 37 kDa
Gen-ID
6696
NCBI Accession
NP_001238759
UniProt
P10451
Pathways
Regulation of Cell Size
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