SPIB Antikörper (AA 200-250)

Produktnummer ABIN5690267

Dieses Anti-SPIB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SPIB in WB, ELISA und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für SPIB Antikörper (AA 200-250) (ABIN5690267)

Target: SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPIB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SPIB Antikörper

Bindungsspezifität: AA 200-250

Spezifität: SPIB antibody is human, mouse and rat reactive. At least four isoforms of SPIB are known to exist, this antibody will detect all but isoform 3.

Aufreinigung: SPIB antibody is affinity chromatography purified via peptide column.

Immunogen: SPIB antibody was raised against a 17 amino acid peptide near the carboxy terminus of human SPIB.

The immunogen is located within amino acids 200 - 250 of SPIB.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SPIB antibody can be used for detection of SPIB by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SPIB antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: SPIB antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu SPIB

Target: SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))

Andere Bezeichnung: SPIB

Hintergrund: SPIB is a member of the ETS transcription factor family that influences lymphoid development and activity and binds the consensus DNA site GGA (A/T) through a unique winged helix-turn-helix motif known as the ETS domain (1). SPIB is found in hematopoietic cells such as B cells and plasmacytoid dendritic cells (DC) (2,3). It promotes the development of plasmacytoid dendritic cells (pDCs) or natural interferon (IFN)-producing cells. SPIB may be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation (3,4).

Molekulargewicht: Predicted: 19, 25, 29 kDa

Observed: 20 kDa

Gen-ID: 6689

NCBI Accession: NP_003112

UniProt: Q01892