Sin Nombre Virus Glycoprotein 2 (AA 670-720) Antikörper

Produktnummer ABIN5690245

Produktdetails

Target: Sin Nombre Virus Glycoprotein 2

Bindungsspezifität: AA 670-720

Reaktivität: Virus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA

Aufreinigung: Sin Nombre virus glycoprotein 2 antibody is affinity chromatography purified via peptide column.

Immunogen: Sin Nombre virus glycoprotein 2 antibody was raised against a 16 amino acid peptide near the center of the Sin Nombre virus glycoprotein.

The immunogen is located within amino acids 670 - 720 of Sin Nombre Virus Glycoprotein 2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Sin Nombre virus glycoprotein 2 antibody can detect 10 ng Sin Nombre virus glycoprotein 2 peptide in ELISA at 1 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Sin Nombre virus glycoprotein 2 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Sin Nombre Glycoprotein 2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Antigendetails

Target: Sin Nombre Virus Glycoprotein 2

Substanzklasse: Viral Protein

Hintergrund: Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1). Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins G1 (Gn) and G2 (Gc). While the G1 glycoprotein is is thought to be degraded by the host autophagy machinery, and this autophagic clearance is required for efficient virus repliaction (2), no such degradation was observed for the G2 glycoprotein.

Gen-ID: 2654026

NCBI Accession: NP_941974

UniProt: Q89905