RNF20 Antikörper (AA 130-180)
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- Target Alle RNF20 Antikörper anzeigen
- RNF20 (Ring Finger Protein 20 (RNF20))
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Bindungsspezifität
- AA 130-180
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RNF20 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- Multiple isoforms of RNF20 are known to exist.
- Aufreinigung
- RNF20 Antibody is affinity chromatography purified via peptide column.
- Immunogen
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RNF20 antibody was raised against a 19 amino acid peptide near the amino terminus of human RNF20.
The immunogen is located within amino acids 130 - 180 of RNF20. - Isotyp
- IgG
- Top Product
- Discover our top product RNF20 Primärantikörper
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- Applikationshinweise
- RNF20 antibody can be used for detection of RNF20 by Western blot at 1 - 2 μ,g/mL.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- RNF20 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- RNF20 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Target
- RNF20 (Ring Finger Protein 20 (RNF20))
- Andere Bezeichnung
- RNF20 (RNF20 Produkte)
- Synonyme
- 4833430L21Rik antikoerper, AW540162 antikoerper, C79397 antikoerper, mKIAA4116 antikoerper, BRE1 antikoerper, BRE1A antikoerper, hBRE1 antikoerper, ring finger protein 20 antikoerper, RNF20 antikoerper, Rnf20 antikoerper
- Hintergrund
- RNF20 Antibody: RNF20 is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. RNF20 selectively suppresses the expression of some genes such as several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). In contrast, RNF20 also positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. Together with the deubiquitinase USP44, RNF20 regulates stem cell differentiation by modulating H2B monoubiquitination.
- Molekulargewicht
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Predicted: 99, 107 kDa
Observed: 100, 110 kDa - Gen-ID
- 56254
- NCBI Accession
- NP_062538
- UniProt
- Q5VTR2
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