KIRREL3 Antikörper (AA 20-70)
Kurzübersicht für KIRREL3 Antikörper (AA 20-70) (ABIN5690032)
Target
Alle KIRREL3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 20-70
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Spezifität
- KIRREL3 antibody is human, mouse and rat reactive. At least two isoforms are known to exist, this antibody will detect both isoforms. KIRREL3 antibody is predicted to not cross-react with other members of the KIRREL protein family.
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Aufreinigung
- KIRREL3 antibody is affinity chromatography purified via peptide column.
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Immunogen
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KIRREL3 antibody was raised against a 19 amino acid peptide near the amino terminus of human KIRREL3.
The immunogen is located within amino acids 20 - 70 of KIRREL3. -
Isotyp
- IgG
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Applikationshinweise
- KIRREL3 antibody can be used for detection of KIRREL3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- KIRREL3 antibody is supplied in PBS containing 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- KIRREL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- KIRREL3 (Kin of IRRE Like 3 (KIRREL3))
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Andere Bezeichnung
- KIRREL3
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Hintergrund
- KIRREL3, also known as nephrin-like protein 2, is a type I transmembrane protein belonging to a family of three podocin interacting proteins and the immunoglobulin superfamily (1). KIRREL3 is involved in the regulation of both glomerular and neural development (2), and more specifically, the nucleogenesis of the pontine nuclei in the developing hindbrain (3). KIRREL3 has also been shown to interact with the synaptic scaffold protein calmodulin-associated serine/threonine kinase (CASK) in neuronal cells (4).
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Molekulargewicht
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Predicted: 64, 84 kDa
Observed: 60 kDa -
Gen-ID
- 84623
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NCBI Accession
- NP_115920
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UniProt
- Q8IZU9
Target
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