KIRREL3 antibody is human, mouse and rat reactive. At least two isoforms are known to exist, this antibody will detect both isoforms. KIRREL3 antibody is predicted to not cross-react with other members of the KIRREL protein family.
Aufreinigung
KIRREL3 antibody is affinity chromatography purified via peptide column.
Immunogen
KIRREL3 antibody was raised against a 19 amino acid peptide near the amino terminus of human KIRREL3.
The immunogen is located within amino acids 20 - 70 of KIRREL3.
KIRREL3
Reaktivität: Maus
FACS, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
Alexa Fluor 350
Applikationshinweise
KIRREL3 antibody can be used for detection of KIRREL3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
KIRREL3 antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
KIRREL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
KIRRE antikoerper, MRD4 antikoerper, NEPH2 antikoerper, PRO4502 antikoerper, 1500010O20Rik antikoerper, 2900036G11Rik antikoerper, SST4 antikoerper, mKIAA1867 antikoerper, kirre like nephrin family adhesion molecule 3 antikoerper, kin of IRRE like 3 (Drosophila) antikoerper, KIRREL3 antikoerper, Kirrel3 antikoerper
Hintergrund
KIRREL3, also known as nephrin-like protein 2, is a type I transmembrane protein belonging to a family of three podocin interacting proteins and the immunoglobulin superfamily (1). KIRREL3 is involved in the regulation of both glomerular and neural development (2), and more specifically, the nucleogenesis of the pontine nuclei in the developing hindbrain (3). KIRREL3 has also been shown to interact with the synaptic scaffold protein calmodulin-associated serine/threonine kinase (CASK) in neuronal cells (4).