IL17RA Antikörper (AA 150-200)

Produktnummer ABIN5690002

Der Kaninchen Polyklonal anti-IL17RA Antikörper wird verwendet zum Nachweis von IL17RA in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IF und IHC (p).

Kurzübersicht für IL17RA Antikörper (AA 150-200) (ABIN5690002)

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL17RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-IL17RA Antikörper

Bindungsspezifität: AA 150-200

Spezifität: IL-17RA antibody is human, mouse and rat reactive. Multiple isoforms of IL-17RA are known to exist. This antibody is predicted to not cross-react with other IL-17 receptor subunits.

Aufreinigung: IL-17RA Antibody is affinity chromatography purified via peptide column.

Immunogen: IL-17RA antibody was raised against an 18 amino acid peptide near the amino terminus of human IL-17RA.

The immunogen is located within amino acids 150 - 200 of IL-17RA.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IL-17RA antibody can be used for detection of IL-17RA by Western blot at 1 - 2 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: IL-17RA Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: IL-17RA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Andere Bezeichnung: IL-17RA

Hintergrund: IL-17RA Antibody: Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes (1). It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F (1,2). IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis (3,4). Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections (5).

Molekulargewicht: Predicted: 95 kDa

Observed: 135 kDa

Gen-ID: 23765

NCBI Accession: NP_055154

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interaktom