IFIT3 Antikörper (AA 380-430)
Kurzübersicht für IFIT3 Antikörper (AA 380-430) (ABIN5689996)
Target
Alle IFIT3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 380-430
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Spezifität
- IFIT3 antibody is human specific. This antibody is predicted to not cross-react with other members of the IFIT protein family.
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Aufreinigung
- IFIT3 antibody is affinity chromatography purified via peptide column.
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Immunogen
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IFIT3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IFIT3.
The immunogen is located within amino acids 380 - 430 of IFIT3 . -
Isotyp
- IgG
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Applikationshinweise
- IFIT3 antibody can be used for detection of IFIT3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- IFIT3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- IFIT3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- IFIT3 (Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3))
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Andere Bezeichnung
- IFIT3
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Hintergrund
- The interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) protein is a member of a family of tetratricopeptide repeat-containing proteins whose transcription is upregulated by interferons, virus infection, and molecular patterns such as dsRNA or lipopolysaccharides (1,2). These proteins have been suggested to induce anti-viral cellular activities in response to infection (2). IFIT3 has been shown to interact with TBK1 following RNA virus infection, thereby bridging TBK1 to VISA on the mitochondrion and activating IRF3 and thus the immune response (3).
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Molekulargewicht
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Predicted: 54 kDa
Observed: 50 kDa -
Gen-ID
- 3437
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NCBI Accession
- NP_001026853
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UniProt
- O14879
Target
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