DNAJC13 Antikörper (AA 1940-1990)

Produktnummer ABIN5689948

Der Kaninchen Polyklonal anti-DNAJC13 Antikörper wird verwendet zum Nachweis von DNAJC13 in Proben von Human und Maus. Er wurde validiert für WB, ELISA und IHC (p).

Kurzübersicht für DNAJC13 Antikörper (AA 1940-1990) (ABIN5689948)

Target: DNAJC13 (DnaJ heat shock protein family (Hsp40) member C13 (DNAJC13))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAJC13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DNAJC13 Antikörper

Bindungsspezifität: AA 1940-1990

Spezifität: DNAJC13 antibody is human and mouse reactive. At least two siforms of DNAJC13 are known to exist, this antibody will detect both isoforms. DNAJC13 antibody is predicted to not cross-react with other DNAJC family members.

Aufreinigung: DNAJC13 antibody is affinity chromatography purified via peptide column.

Immunogen: DNAJC13 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DNAJC13.

The immunogen is located within amino acids 1940 - 1990 of DNAJC13.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: DNAJC13 antibody can be used for detection of DNAJC13 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: DNAJC13 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: DNAJC13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu DNAJC13

Target: DNAJC13 (DnaJ heat shock protein family (Hsp40) member C13 (DNAJC13))

Andere Bezeichnung: DNAJC13

Hintergrund: DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C. elegans (1). It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system. Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles (2). DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor (3).

Molekulargewicht: Predicted: 249 kDa

Observed: 249 kDa

Gen-ID: 23317

NCBI Accession: NP_056083

UniProt: O75165