BimEL Antikörper (AA 20-70)

Produktnummer ABIN5689905

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch BimEL in ELISA, ICC, IF und WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für BimEL Antikörper (AA 20-70) (ABIN5689905)

Target: BimEL

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BimEL Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)

Produktdetails anti-BimEL Antikörper

Bindungsspezifität: AA 20-70

Spezifität: Bim EL antibody is human and mouse reactive. Multiple isoforms of Bim are known to exist, this antibody only detects the Bim EL isoform.

Aufreinigung: Bim EL Antibody is affinity chromatography purified via peptide column.

Immunogen: Bim EL antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Bim.

The immunogen is located within amino acids 20 - 70 of Bim EL.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Bim EL antibody can be used for detection of Bim EL by Western blot at 1 - 2 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Bim EL Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Bim EL antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu BimEL

Target: BimEL

Andere Bezeichnung: Bim EL

Hintergrund: Bim EL Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim, also known as Bcl-2-like protein 11, is a pro-apoptotic member of this family and interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Multiple isoforms of Bim are known to exist, with Bim EL being the longest isoform (1,2).

Molekulargewicht: Predicted: 22 kDa

Observed: 24 kDa

Gen-ID: 10018

NCBI Accession: NP_619527

UniProt: O43521