ITGA4 Antikörper (AA 1024-1028)

Produktnummer ABIN5689252

Der Kaninchen Polyklonal Anti-ITGA4-Antikörper wurde für WB validiert. Er ist geeignet, ITGA4 in Proben von Human zu detektieren.

Kurzübersicht für ITGA4 Antikörper (AA 1024-1028) (ABIN5689252)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ITGA4 Antikörper

Bindungsspezifität: AA 1024-1028

Spezifität: This antibody detects endogenous level of total LPAM-1(Integrin α,4, CD49d) protein.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: LPAM-1 (Integrin a4, CD49d) antibody was raised against a peptide sequence around aa.1024~1028 (Y-I-N-S-K) derived from Human LPAM-1 (Integrin α,4, CD49d).

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Andere Bezeichnung: LPAM 1

Hintergrund: Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.

Molekulargewicht: 70, 140, 180 kDa

Gen-ID: 3676

NCBI Accession: NP_000876

UniProt: P13612

Pathways: Integrin Complex