SAPK, JNK (AA 181-185) Antikörper

Produktnummer ABIN5689246

Produktdetails

Target: SAPK, JNK

Bindungsspezifität: AA 181-185

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Spezifität: This antibody detects endogenous level of total SAPK/JNK protein.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: SAPK/JNK (Ab-183) antibody was raised against a peptide sequence around aa.181~185 (M-M-T-P-Y) derived from Human SAPK/JNK.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Antigendetails

Target: SAPK, JNK

Andere Bezeichnung: SAPK / JNK

Synonyme: JNK-55 antikoerper, JNK2 antikoerper, JNK2A antikoerper, JNK2ALPHA antikoerper, JNK2B antikoerper, JNK2BETA antikoerper, PRKM9 antikoerper, SAPK antikoerper, SAPK1a antikoerper, p54a antikoerper, p54aSAPK antikoerper, AI851083 antikoerper, Prkm9 antikoerper, mitogen-activated protein kinase 9 antikoerper, MAPK9 antikoerper, Mapk9 antikoerper

Hintergrund: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.

Molekulargewicht: 46, 54 kDa

Gen-ID: 5601

NCBI Accession: NP_001128516

UniProt: P45984, P53779