SAPK, JNK (AA 181-185) Antikörper
Kurzübersicht für SAPK, JNK (AA 181-185) Antikörper (ABIN5689246)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 181-185
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Spezifität
- This antibody detects endogenous level of total SAPK/JNK protein.
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Aufreinigung
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogen
- SAPK/JNK (Ab-183) antibody was raised against a peptide sequence around aa.181~185 (M-M-T-P-Y) derived from Human SAPK/JNK.
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Applikationshinweise
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store antibody at -20°C for up to one year.
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- SAPK, JNK
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Andere Bezeichnung
- SAPK / JNK
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Hintergrund
- Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.
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Molekulargewicht
- 46, 54 kDa
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Gen-ID
- 5601
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NCBI Accession
- NP_001128516
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UniProt
- P45984, P53779
Target
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