Synaptotagmin Antikörper (Ser309)

Produktnummer ABIN5688918

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Synaptotagmin in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Ratte, Maus und Human.

Kurzübersicht für Synaptotagmin Antikörper (Ser309) (ABIN5688918)

Target: Synaptotagmin (SYT)

Reaktivität: Ratte, Maus, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Synaptotagmin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Synaptotagmin Antikörper

Bindungsspezifität: Ser309

Spezifität: Synaptotagmin antibody is specific for Mr 60 - 62k synaptotagmin phosphorylated at Ser309.

Aufreinigung: Affinity Purified

Immunogen: Synaptotagmin (Ser309) polyclonal antibody was raised against a synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho Ser309 of synaptotagmin.

Anwendungsinformationen

Applikationshinweise: Applications include Dot Blots (DB) and Western Blots (WB). Suitability for Immunohistochemistry (IHC) has not yet been determined. Human, mouse, and rat have 100 % amino acid sequence identity with the antigen used to raise the antibody. When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: For long term storage -80°C is recommended, but shorter term storage at -20°C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year.

Details zu Synaptotagmin

Target: Synaptotagmin (SYT)

Andere Bezeichnung: Synaptotagmin

Hintergrund: Synaptotagmin is widely regarded as the primary calcium sensor for synaptic vesicle exocytosis. Moreover recent studies indicate that the protein also plays a key role in endocytosis. Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin ability to influence both the exocytotic and endocytotic components of synaptic transmission.

Molekulargewicht: 60/62 kDa

Gen-ID: 25716

UniProt: P21707