DLG4 Antikörper (N-Term)

Produktnummer ABIN5688879

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DLG4 in WB. Es zeigt Reaktivität gegenüber Proben von Ratte, Human, Maus, Rind (Kuh) und Zebrafisch (Danio rerio).

Kurzübersicht für DLG4 Antikörper (N-Term) (ABIN5688879)

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Reaktivität: Ratte, Human, Maus, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLG4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DLG4 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Affinity Purified

Immunogen: Peptide corresponding to amino acid residues from the N-terminal region of rat PSD-95, conjugated to keyhole limpet hemocyanin (KLH).

Anwendungsinformationen

Applikationshinweise: The antibody has been directly tested for reactivity in Western blots in rat and mouse tissues. It is anticipated that the antibody will also work with bovine, human, mouse, non-human primates and zebra fish tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: PSD-95 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Details zu DLG4

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Andere Bezeichnung: PSD-95

Hintergrund: PSD-95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses (Kim and Sheng, 2004). Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation (Chung et al., 2004).

Molekulargewicht: 95 kDa

Gen-ID: 29495

UniProt: P31016

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity