SLC6A1 Antikörper (C-Term)

Produktnummer ABIN5688853

Der Kaninchen Polyklonal Anti-SLC6A1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, SLC6A1 in Proben von Ratte und Maus zu detektieren.

Kurzübersicht für SLC6A1 Antikörper (C-Term) (ABIN5688853)

Target: SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC6A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SLC6A1 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Affinity Purified

Immunogen: Peptide corresponding to amino acid residues from the C-terminal region of rat GAT-1.

Anwendungsinformationen

Applikationshinweise: The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will also react with mouse tissue based on the fact that this species has 100 % homology with the amino acid sequence used as antigen.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: GAT-1 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Details zu SLC6A1

Target: SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

Andere Bezeichnung: GAT-1

Hintergrund: Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia (Minelli et al., 1995). GAT-1 is thought to play a key role in epileptogenesis (Zhao et al. 2003).

Molekulargewicht: 67 kDa

Gen-ID: 79212

UniProt: P23978