NEFM Antikörper (C-Term)
Kurzübersicht für NEFM Antikörper (C-Term) (ABIN5688746)
Target
Alle NEFM Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- C-Term
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Spezifität
- Specific for the ~145k Neurofilament M protein.
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Aufreinigung
- Total IgG fraction
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Immunogen
- Recombinant fusion protein containing the extreme C-terminus of rat NF-M expressed in and purified from E. coli.
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Neurofilament NF-M antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
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- NEFM (Neurofilament Triplet M Protein (NEFM))
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Andere Bezeichnung
- Neurofilament NF-M
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Hintergrund
- Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease.
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Molekulargewicht
- 145 kDa
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Gen-ID
- 24588
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UniProt
- P12839
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Pathways
- Brown Fat Cell Differentiation
Target
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