NEFM
Reaktivität: Human
WB, IF
Wirt: Kaninchen
Monoclonal
unconjugated
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Lagerung
-20 °C
Informationen zur Lagerung
Neurofilament NF-M antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
Target
NEFM
(Neurofilament Triplet M Protein (NEFM))
Andere Bezeichnung
Neurofilament NF-M
Hintergrund
Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease.