Retinoid X Receptor Antikörper

Produktnummer ABIN5688670

Der Maus Monoklonal anti-Retinoid X Receptor Antikörper wird verwendet zum Nachweis von Retinoid X Receptor in Proben von Human, Maus, Ratte und Rind (Kuh). Er wurde validiert für WB.

Kurzübersicht für Retinoid X Receptor Antikörper (ABIN5688670)

Target: Retinoid X Receptor

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Applikation: Western Blotting (WB)

Klon: 1373

Produktdetails

Aufreinigung: Protein G purified

Immunogen: Hinge peptide from human retinoid X receptor, y-isotype.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: The antibody has been directly tested for reactivity in Western blots in human tissues. It is anticipated that the antibody will also work with bovine, mouse, non-human primate and rat tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Retinoid X Receptor antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Antigendetails

Target: Retinoid X Receptor

Hintergrund: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X Receptors (RXRs) family (RXRalpha, beta and gamma) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).

Molekulargewicht: 48 kDa

Gen-ID: 6258

UniProt: P48443