Retinoic Acid Receptor gamma Antikörper (N-Term)

Produktnummer ABIN5688663

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Retinoic Acid Receptor gamma in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Hund und Rind (Kuh).

Kurzübersicht für Retinoic Acid Receptor gamma Antikörper (N-Term) (ABIN5688663)

Target: Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

Reaktivität: Human, Maus, Hund, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Retinoic Acid Receptor gamma Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 763

Produktdetails anti-Retinoic Acid Receptor gamma Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Protein G purified

Immunogen: Peptide corresponding to amino acid residues from the N-terminal region of human retinoic acid receptor, a-isotype.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: The antibody has been directly tested for reactivity in Western blots in human tissues. It is anticipated that the antibody will also work with bovine, canine and mouse tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Retinoic Acid Receptor antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Details zu Retinoic Acid Receptor gamma

Target: Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

Andere Bezeichnung: Retinoic Acid Receptor

Hintergrund: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXRalpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).

Molekulargewicht: 48 kDa

Gen-ID: 5914

UniProt: P10276

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Cell Size