Retinoic Acid Receptor gamma Antikörper (N-Term)

Produktnummer ABIN5688662

Dieses Anti-Retinoic Acid Receptor gamma-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Retinoic Acid Receptor gamma in WB. Geeignet für Human, Maus, Ratte, Hund und Ziege.

Kurzübersicht für Retinoic Acid Receptor gamma Antikörper (N-Term) (ABIN5688662)

Target: Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

Reaktivität: Human, Maus, Ratte, Hund, Ziege

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Retinoic Acid Receptor gamma Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 336

Produktdetails anti-Retinoic Acid Receptor gamma Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Protein G purified

Immunogen: Peptide corresponding to amino acids from N-terminal region of human retinoic acid receptor, b-isotype.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: The antibody has been directly tested for reactivity in Western blots in human tissues. It is anticipated that the antibody will also work with canine, guinea pig, mouse and rat tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Retinoic Acid Receptor antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Details zu Retinoic Acid Receptor gamma

Target: Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

Andere Bezeichnung: Retinoic Acid Receptor

Hintergrund: Retinoic Acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X receptors (RXRs) family (RXRalpha, beta and gamma) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors (RARs). RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).

Molekulargewicht: 48 kDa

Gen-ID: 5915

UniProt: P10826

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Cell Size