ARHGDIA Antikörper (Internal Region)

Produktnummer ABIN568700

Produktdetails anti-ARHGDIA Antikörper

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ARHGDIA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-QLAQIAAENE

Spezifität: Recognizes ARHGDIA.

Kreuzreaktivität (Details): Species reactivity (expected):Human, Dog, Cow.
Species reactivity (tested):Mouse, Rat.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequencefrom the internal region of the protein sequence according to NP_004300.1. Genename: ARHGDIA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ARHGDIA

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Andere Bezeichnung: ARHGDIA / GDIA1 (ARHGDIA Produkte)

Synonyme: GDIA1 antikoerper, NPHS8 antikoerper, RHOGDI antikoerper, RHOGDI-1 antikoerper, Bles01 antikoerper, zgc:55554 antikoerper, zgc:77681 antikoerper, wu:fa96g11 antikoerper, ARHGDIA antikoerper, NV15502 antikoerper, 5330430M07Rik antikoerper, Gdi-1 antikoerper, Rho-GDI antikoerper, RhoDGI antikoerper, RhoGDI-1 antikoerper, arhgdia antikoerper, MGC84535 antikoerper, gdia1 antikoerper, rhogdi antikoerper, rhogdi-1 antikoerper, rhogdi1 antikoerper, Rho GDP dissociation inhibitor alpha antikoerper, Rho GDP dissociation inhibitor (GDI) alpha antikoerper, rho GDP-dissociation inhibitor 2 antikoerper, Rho GDP dissociation inhibitor (GDI) alpha L homeolog antikoerper, ARHGDIA antikoerper, Arhgdia antikoerper, arhgdia antikoerper, LOC100120432 antikoerper, arhgdia.L antikoerper

Hintergrund: Rho GDP-dissociation inhibitor 1, also known ARHGDIA, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. Localized to the cytoplasm, ARHGDIA inhibits the dissociation of GDP from Rho proteins, thereby preventing GTP from binding to and subsequently activating Rho proteins. In humans ARHGDIA can be phosphorylated at Ser 101 by p21-activated kinase, an event that inhibits ARHGDIA activity and may result in positive feedback regulation of certain ARHGDIA target proteins.Synonyms: Rho GDI 1, Rho GDP-dissociation inhibitor 1, Rho-GDI alpha, RhoGDI1

Gen-ID: 396

NCBI Accession: NP_004300

UniProt: P52565

Pathways: Neurotrophin Signalübertragung