UGDH Antikörper (Biotin)
Kurzübersicht für UGDH Antikörper (Biotin) (ABIN568500)
Target
Alle UGDH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- The reagents were evaluated for potency, purity and specificity using most or all of the following techniques: Immunoelectrophoresis, Cross-Immunoelectrophoresis, single Radial Immunodiffusion (Ouchterlony), block titration, ELISA, Immunoblotting and Enzyme Inhibition. Cross-reactivities against enzymes of other sources may occur but have not been determined.
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Produktmerkmale
- Molar Ratio: Biotin/IgG ~5.2
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Aufreinigung
- Ammonium Sulphate Precipitation and Ion Exchange Chromatography
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Immunogen
- Uridine-5’-Diphosphoglucose Dehydrogenase isolated and purified from Bovine liver. Freund’s complete adjuvant is used in the first step of the immunization procedure.
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Rekonstitution
- Restore by adding 1.0 mL of sterile distilled water
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Konzentration
- 10.0 mg/mL
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Buffer
- PBS, pH 7.2 without preservatives and foreign proteins
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Konservierungsmittel
- Without preservative
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody lyophilized at 2-8 °C and reconstituted at 2-8 °C for one week or (in aliquots) at -20 °C for longer. If a slight precipitation occurs upon storage, this should be removed by centrifugation.
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- UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))
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Andere Bezeichnung
- UGDH
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Hintergrund
- UGDH is a member of the UDP-glucose/GDP-mannose dehydrogenase family and is a ubiquitously expressed protein most abundant in the liver. This protein converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis.Synonyms: UDP-Glc dehydrogenase, UDP-GlcDH, UDP-glucose 6-dehydrogenase, UDPGDH
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Gen-ID
- 281564
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NCBI Accession
- NP_776636
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UniProt
- P12378
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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