PTPRD Antikörper (AA 1077-1265)
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- Target Alle PTPRD Antikörper anzeigen
- PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))
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Bindungsspezifität
- AA 1077-1265
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PTPRD Antikörper ist unkonjugiert
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Applikation
- ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- PTPRD Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human PTPRD (AA: 1077-1265) expressed in E. Coli.
- Klon
- 5H5D7
- Isotyp
- IgG1
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))
- Andere Bezeichnung
- PTPRD (PTPRD Produkte)
- Hintergrund
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Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.
Aliases: HPTP, PTPD, HPTPD, HPTPDELTA, RPTPDELTA
- Molekulargewicht
- 214.8kDa
- Gen-ID
- 5789
- HGNC
- 2204
- UniProt
- P23468
- Pathways
- Synaptic Membrane
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