HAase Antikörper

Produktnummer ABIN568255

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HAase in WB, IP, IF, DB, EIA, ID und RIA. Er zeigt eine Reaktivität gegenüber Schaf.

Kurzübersicht für HAase Antikörper (ABIN568255)

Target: HAase (Hyaluronidase (HAase))

Reaktivität: Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HAase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Dot Blot (DB), Enzyme Immunoassay (EIA), Immunodiffusion (ID), Radioimmunoassay (RIA)

Produktdetails anti-HAase Antikörper

Aufreinigung: Ammonium Sulphate Precipitation and Ion Exchange Chromatography.

Immunogen: Hyaluronidase isolated and purified from Sheep testes. Freund’s complete adjuvant is used in the first step of the immunization procedure.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore by adding 1.0 mL sterile distilled water.

Konzentration: 10.0 mg/mL

Buffer: PBS, pH 7.2 without preservatives and foreign proteins.

Konservierungsmittel: Without preservative

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody lyophilized at 2-8 °C and reconstituted at 2-8 °C for one week or (in aliquots) at -20 °C for longer. If a slight precipitation occurs upon storage, this should be removed by centrifugation.

Details zu HAase

Target: HAase (Hyaluronidase (HAase))

Andere Bezeichnung: Hyaluronidase

Hintergrund: Hyaluronidase degrades hyaluronic acid, which is an important structural proteoglycan found in basement membranes and also extracellular matrices. There are six members of the hyaluronidase family. Hyaluronidase PH20 is a GPI-anchored enzyme located on the human sperm surface and inner acrosomal membrane and plays a role in sperm penetration through the the hyaluronic acid-rich cumulus cell layer surrounding the oocyte. Abnormal expression of this gene has been implicated in degradation of basement membranes leading to tumor invasion and metastasis.Synonyms: HYAL-1, HYAL1, HYAL2, Hyal-2, Hyaluronidase, Hyaluronoglucosaminidase, LUCA-1, LUCA1

Pathways: Glycosaminoglycan Metabolic Process