GUK1 Antikörper (Biotin)

Produktnummer ABIN568250

Produktdetails anti-GUK1 Antikörper (Biotin)

Target: GUK1 (Guanylate Kinase 1 (GUK1))

Reaktivität: Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GUK1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Dot Blot (DB), Enzyme Immunoassay (EIA), Immunodiffusion (ID), Radioimmunoassay (RIA)

Produktmerkmale: Molar Ratio: Biotin/IgG = ~6.6

Aufreinigung: Ammonium Sulphate Precipitation and Ion Exchange Chromatography.

Immunogen: Guanylate kinase isolated and purified from Porcine brain. Freund’s complete adjuvant is used in the first step of the immunization procedure.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore by adding 1.0 mL sterile distilled water.

Konzentration: 10.0 mg/mL

Buffer: PBS, pH 7.2 without preservatives and foreign proteins.

Konservierungsmittel: Without preservative

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody lyophilized at 2-8 °C and reconstituted at 2-8 °C for one week or (in aliquots) at -20 °C for longer. If a slight precipitation occurs upon storage, this should be removed by centrifugation.

Details zu GUK1

Target: GUK1 (Guanylate Kinase 1 (GUK1))

Andere Bezeichnung: Guanylate Kinase / GUK1 (GUK1 Produkte)

Synonyme: GMK antikoerper, AA409738 antikoerper, AL033299 antikoerper, AL033300 antikoerper, AV026611 antikoerper, Gmk antikoerper, Guk-1 antikoerper, guk1 antikoerper, zgc:73128 antikoerper, zgc:73217 antikoerper, gmk antikoerper, GUK1 antikoerper, AGK1 antikoerper, T11A7.23 antikoerper, guanylate kinase 1 antikoerper, DDBDRAFT_0215291 antikoerper, DDBDRAFT_0230100 antikoerper, DDB_0215291 antikoerper, DDB_0230100 antikoerper, sb:cb295 antikoerper, zgc:86776 antikoerper, guanylate kinase 1 antikoerper, guanylate kinase (GUK1) antikoerper, guanylate kinase antikoerper, guanylate kinase 1b antikoerper, guanylate kinase 1 L homeolog antikoerper, guanylate kinase 1a antikoerper, GUK1 antikoerper, Guk1 antikoerper, guk1b antikoerper, guk1 antikoerper, guk1.L antikoerper, GK-1 antikoerper, gmk antikoerper, gmkA antikoerper, Mrub_2093 antikoerper, Arnit_0783 antikoerper, Ndas_3097 antikoerper, Mesil_1319 antikoerper, Slip_0854 antikoerper, Olsu_0986 antikoerper, Acear_1451 antikoerper, AOR_1_2886174 antikoerper, guk1a antikoerper

Hintergrund: Guanylate kinase catalyzes the transfer of phosphate from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) or dGMP. This enzyme functions in the recovery of cGMP and is, therefore, thought to regulate the supply of guanine nucleotides to signal transduction pathways. The GUK2 and GUK3 isoforms are determined by separate loci. Brady et al. (1996) cloned human and mouse cDNAs of GUK1. They stated that the guanylate kinases are targets for cancer chemotherapy and are inhibited by the antitumor drug 6-thioguanine. They reported that the human gene codes for a protein of 197 amino acids with a mass of 21.7 kD. They found that the 1-kb message was ubiquitously expressed.Synonyms: GMK, GMP kinase

Gen-ID: 9823

UniProt: P31006

Pathways: Nucleotide Phosphorylation, ER-Nucleus Signaling, Ribonucleoside Biosynthetic Process