Glutathione Reductase Antikörper (Biotin)

Produktnummer ABIN568226

Produktdetails anti-Glutathione Reductase Antikörper (Biotin)

Target: Glutathione Reductase (GSR)

Reaktivität: Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutathione Reductase Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Enzyme Immunoassay (EIA), Dot Blot (DB), Immunodiffusion (ID), Radioimmunoassay (RIA)

Spezifität: The antibody recognizes Glutathione Reductase from Baker's yeast. The reagents were evaluated for potency, purity and specificity using most or all of the following techniques: Immunoelectrophoresis, Cross-Immunoelectrophoresis, single Radial Immunodiffusion (Ouchterlony), block titration, ELISA, Immunoblotting and Enzyme Inhibition. Cross-reactivities against enzymes of other sources may occur but have not been determined.

Produktmerkmale: Molar Ratio: Biotin/IgG ~6.2

Aufreinigung: Ammonium Sulphate Precipitation and Ion Exchange Chromatography

Immunogen: Glutathione Reductase isolated and purified from Baker's Yeast. Freund’s complete adjuvant is used in the first step of the immunization procedure.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore by adding 1.0 mL of sterile distilled water

Konzentration: 10.0 mg/mL

Buffer: PBS, pH 7.2 without preservatives and foreign proteins

Konservierungsmittel: Without preservative

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody lyophilized at 2-8 °C and reconstituted at 2-8 °C for one week or (in aliquots) at -20 °C for longer. If a slight precipitation occurs upon storage, this should be removed by centrifugation.

Details zu Glutathione Reductase

Target: Glutathione Reductase (GSR)

Andere Bezeichnung: Glutathione Reductase (GSR Produkte)

Synonyme: GR antikoerper, ATGR2 antikoerper, EMB2360 antikoerper, glutathione reductase antikoerper, AI325518 antikoerper, D8Ertd238e antikoerper, Gr-1 antikoerper, Gr1 antikoerper, DDBDRAFT_0168952 antikoerper, DDBDRAFT_0231410 antikoerper, DDB_0168952 antikoerper, DDB_0231410 antikoerper, 2151 antikoerper, CG2151 antikoerper, DTR antikoerper, Dm-TrxR antikoerper, DmTR antikoerper, DmTrx antikoerper, DmTrxR antikoerper, DmTrxR-1 antikoerper, Dmel\\CG2151 antikoerper, Gr antikoerper, Trx antikoerper, TrxR antikoerper, TrxR-1 antikoerper, Trxr1 antikoerper, anon-WO03040301.185 antikoerper, anon-WO03040301.187 antikoerper, dTrxR antikoerper, dmtrxr-1 antikoerper, gr antikoerper, l(1)G0154 antikoerper, l(1)G0379 antikoerper, l(1)G0477 antikoerper, l(1)G0481 antikoerper, trxr-1 antikoerper, gor1 antikoerper, glutathione reductase, gro-2 antikoerper, glutathione reductase antikoerper, glutathione-disulfide reductase antikoerper, GR; GRase antikoerper, mitochondrial glutathione reductase Pgr1 antikoerper, Glutathione reductase (GR) (GRase) antikoerper, Thioredoxin reductase-1 antikoerper, glutathione-disulfide reductase family protein antikoerper, glutathione reductase 1 antikoerper, GR antikoerper, gor antikoerper, GSR antikoerper, GSR1 antikoerper, Gsr_2 antikoerper, Gsr antikoerper, GSHR1 antikoerper, gsr antikoerper, LbGR antikoerper, pgr1 antikoerper, GSHR2 antikoerper, GLR2 antikoerper, Bcen_2392 antikoerper, RPE_1989 antikoerper, HCAG_02219 antikoerper, SJAG_01162 antikoerper, Trxr-1 antikoerper, PF14_0192 antikoerper, POPTR_0001s14480g antikoerper, gsr1 antikoerper

Hintergrund: Glutathione reductase (GR) is a member of pyridine nucleotide-disulfideoxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione(GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG): GSSG + NADPH + H+ ?2GSH + NADP+. In mosteukaryotic cells, GR maintains the ratio of [GSH]/[GSSG], and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.Synonyms: GLUR, GR, GRD1, GRase, GSR

Gen-ID: 856014

NCBI Accession: NP_015234

UniProt: P41921

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis