AGE Antikörper

Produktnummer ABIN5680158

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch AGE in ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für AGE Antikörper (ABIN5680158)

Target: AGE (Advanced Glycation End Products (AGE))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGE Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-AGE Antikörper

Spezifität: Advanced Glycation End Products (AGE), cross-reactivity BSA-AGE, HSA-AGE <1 %

Kreuzreaktivität (Details): Human, rat. Broad reactivity with advanced glycation end products (AGE) in many species.

Produktmerkmale: This antibody is suitable for the detection of different AGE products in tissues, tissue extracts and body fluids. Long-term incubation of proteins with glucose leads, through Schiff's base and Amadori rearrangement products, to the formation of advanced glycation end products (AGE) which are characterized by fluorescence, brown color and inter- and intra-molecular cross-linking. Recent immunological studies using anti-AGE antibodies demonstrated the presence of AGE in (i) human lens, (ii) renal proximal tubules in patients with diabetic nephropathy and chronic renal failure, (iii) atherosclerotic lesions of arterial walls, (iv) ß2-microglobulin of carpal tunnel amyloid fibril deposits in patients with hemodialysis-related amyloidosis and (v) brain tissues of patients with Alzheimer's disease. These results suggested the potential role of AGE in normal aging and age-enhanced disease processes. Advanced Glycation End Products (AGE), cross-reactivity BSA and HSA <1 % .

Aufreinigung: Protein A affinity purified IgG

Immunogen: Advanced Glycation End Products /BSA/HSA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: human lens, arteriosclerotic plaques,ELISA, IHC not established,60 min at RT or 18 hr at 2-8 °C,(liquid conc.) ELISA app. 1 μg/mL, (IHC 5-10 μg/mL)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS 0.05 M,  pH 7.15, 0.85 % NaCl, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu AGE

Target: AGE (Advanced Glycation End Products (AGE))

Andere Bezeichnung: AGE, Advanced Glycation End Products

Substanzklasse: Chemical