SELPLG Antikörper (PE)

Produktnummer ABIN567645

Dieses Anti-SELPLG-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von SELPLG in FACS. Geeignet für Human.

Kurzübersicht für SELPLG Antikörper (PE) (ABIN567645)

Target: SELPLG (Selectin P Ligand (SELPLG))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SELPLG Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: TC2

Produktdetails anti-SELPLG Antikörper (PE)

Spezifität: This antibody reacts with CD162, a 220 kDa type I integral membrane protein expressed as disulfide-linked homodimer (sialomucin family). CD162 is present on the most peripheral blood T lymphocytes, monocytes, granulocytes, it is also expressed on a subpopulation of B lymphocytes and CD34+ bone marrow cells.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Size-Exclusion Chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline (PBS), 15 mM Sodium Azide, 0.2 % (w/v) high-grade protease free BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu SELPLG

Target: SELPLG (Selectin P Ligand (SELPLG))

Andere Bezeichnung: CD162 / PSGL1

Hintergrund: CD162 (P-selectin glycoprotein ligand-1, PSGL-1) is a sialomucin constitutively expressed as a disulfide-linked homodimer of two 120 kDa subunits on the surface of circulating leukocytes. CD162 serves as a ligand for P- E- and L-selectin, with the highest affinity for P-selectin. It is thus involved in leukocyte rolling at the endothelial surfaces, prerequisite for firm leukocyte adhesion and subsequent transendothelial migration. CD162 also mediates leukocyte-platelet adhesion and interleukocyte contacts. Whereas serving as an adhession molecule on mature leukocytes, CD162 is a potent negative regulator of human hematopoietic progenitors.Synonyms: P-selectin glycoprotein ligand 1, PSGL-1, SELPLG, Selectin P ligand

Gen-ID: 6404