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NQO2 Antikörper

Dieses Anti-NQO2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von NQO2 in WB und EIA. Geeignet für Human und Maus.
Produktnummer ABIN567621

Kurzübersicht für NQO2 Antikörper (ABIN567621)

Target

Alle NQO2 Antikörper anzeigen
NQO2

Reaktivität

  • 55
  • 42
  • 25
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 59
  • 7
  • 2
Maus

Klonalität

  • 53
  • 15
Monoklonal

Konjugat

  • 36
  • 6
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser NQO2 Antikörper ist unkonjugiert

Applikation

  • 46
  • 38
  • 10
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon

AT1E3
  • Spezifität

    The antibody recognizes human and mouse NQO2. Other species not tested.

    Aufreinigung

    Protein-G affinity chromatography

    Isotyp

    IgG1
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.0 mg/mL

    Buffer

    PBS, pH 7.4, containing 0.09 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target

    NQO2

    Andere Bezeichnung

    NQO2

    Hintergrund

    Quinone oxidoreductase (NQO1 and NQO2) are cytosolic proteins that catalyze metabolic redaction of quinines and derivates.NQO2 is inhibited by flavones such as quercetin. Also benzo(a)pyrene is another known inhibitor of NQO2. Even though overlapping substrates specificities have been observed for NQO1 and NQO2, such as for CB1954 activation, significant differences exist in relative affinities for the various substrates.The detoxification role of NQO2 has not been found, and it has no known endogenous biological substrates. However, NQO1 plays an important role in the detoxification of various endogenous and exogenous quinones, including estrogen quinines. Also NQO2 has a melatonin-binding site, which may explain the anti-oxidant role of melatonin related with circadian rhythm.Synonyms: NMOR2, NRH dehydrogenase [quinone] 2, NRH:quinone oxidoreductase 2, Ribosyldihydronicotinamide dehydrogenase [quinone]

    Gen-ID

    4835
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