BUB1B Antikörper

Produktnummer ABIN567606

Produktdetails anti-BUB1B Antikörper

Target: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BUB1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Spezifität: This antibody reacts with BUBR1 (121 kDa) on Western blotting, Immunoprecipitation and Immunocytochemistry.

Aufreinigung: Protein-A Agarose Chromatography of hybridoma supernatant.

Klon: 8G1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol without preservatives.

Konservierungsmittel: Without preservative

Details zu BUB1B

Target: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Andere Bezeichnung: BUB1B (BUB1B Produkte)

Synonyme: BUB1beta antikoerper, BUBR1 antikoerper, Bub1A antikoerper, MAD3L antikoerper, MVA1 antikoerper, SSK1 antikoerper, hBUBR1 antikoerper, AU045529 antikoerper, bub1b antikoerper, BUB1 antikoerper, BUB1-like antikoerper, BubR1 antikoerper, BubRI antikoerper, CG14030 antikoerper, CG14030/Bub1 antikoerper, Dmel\\CG14030 antikoerper, bub1 antikoerper, BUB1 mitotic checkpoint serine/threonine kinase B antikoerper, BUB1B, mitotic checkpoint serine/threonine kinase antikoerper, BUB1B, mitotic checkpoint serine/threonine kinase L homeolog antikoerper, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta antikoerper, Bub1 kinase antikoerper, BUB1B antikoerper, Bub1b antikoerper, bub1b.L antikoerper, bub1b antikoerper, Bub1 antikoerper

Hintergrund: Metaphase checkpoint controls sense abnormalities in chromosome alignment during mitosis and prevent progression to anaphase until proper alignment has been attained. A number of proteins, including Mitotic arrest deficiency protein 2 (MAD2), Budding uninhibited benzimidazole 1 (BUB1) and Budding uninhibited benzimidazole receptor 1 (BUBR1), have been implicated in the metaphase checkpoint control in mammalian cells. BUB1 and BUBR1 both localize to kinetochores during mitosis, suggesting that they play a role in delaying anaphase until all chromosomes achieve correct, bipolar attachment to the spindle. BUB1 and BUBR1 respond differently to spindle dynamics, they are part of a common complex during mitosis and BUB1 and BUBR1 may integrate different 'spindle assembly signals' into a single signal which can then be interpreted by downstream cell cycle regulators.Synonyms: BUB1 beta, BUBR1, MAD3/BUB1-related protein kinase, MAD3L, Mitotic checkpoint kinase MAD3L, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Protein SSK1

Gen-ID: 701