OMA1 Antikörper (AA 401-500)

Produktnummer ABIN5675734

Der Kaninchen Polyklonal Anti-OMA1-Antikörper wurde für WB, ELISA, IF (cc), IF (p), ICC, IHC (fro) und IHC (p) validiert. Er ist geeignet, OMA1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für OMA1 Antikörper (AA 401-500) (ABIN5675734)

Target: OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OMA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-OMA1 Antikörper

Bindungsspezifität: AA 401-500

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Pig,Horse,Chicken,Cat,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OMA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu OMA1

Target: OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))

Andere Bezeichnung: OMA1

Hintergrund:

Synonyms: Metalloendopeptidase OMA1, mitochondrial, OMA1, Metalloprotease-related protein 1, MPRP-1, Overlapping with the m-AAA protease 1 homolog, OMA1, MPRP1

Background: Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.

Gen-ID: 115209

UniProt: Q96E52