SOX2 Antikörper (AA 221-317) (HRP)

Produktnummer ABIN5675340

Produktdetails anti-SOX2 Antikörper (HRP)

Target: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Bindungsspezifität: AA 221-317

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX2 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SOX2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SOX2

Target: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Andere Bezeichnung: SOX2 (SOX2 Produkte)

Synonyme: ANOP3 antikoerper, MCOPS3 antikoerper, RGD1565646 antikoerper, Sox-2 antikoerper, lcc antikoerper, ysb antikoerper, cb236 antikoerper, wu:fb83g04 antikoerper, wu:fc14d07 antikoerper, zgc:65860 antikoerper, zgc:77389 antikoerper, SRY-box2 antikoerper, Xsox-2 antikoerper, anop3 antikoerper, mcops3 antikoerper, sox-2 antikoerper, SRY-box 2 antikoerper, SRY box 2 antikoerper, SRY (sex determining region Y)-box 2 antikoerper, SRY-box 2 S homeolog antikoerper, SOX2 antikoerper, Sox2 antikoerper, sox2 antikoerper, sox2.S antikoerper

Hintergrund:

Synonyms: Transcription factor SOX-2, SOX2,

Background: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

Gen-ID: 6657

UniProt: P48431

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis