DAPK3 Antikörper (pThr265) (Biotin)

Produktnummer ABIN5675188

Der Kaninchen Polyklonal Anti-DAPK3-Antikörper wurde für WB, ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, DAPK3 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für DAPK3 Antikörper (pThr265) (Biotin) (ABIN5675188)

Target: DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAPK3 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-DAPK3 Antikörper (Biotin)

Bindungsspezifität: pThr265

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthesised phosphopeptide derived from human ZIP Kinase around the phosphorylation site of Thr265

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu DAPK3

Target: DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))

Andere Bezeichnung: ZIP Kinase

Hintergrund:

Synonyms: Death-associated protein kinase 3, DAPK3, DAP kinase 3, Dlk, MYPT1 kinase, Zipper-interacting protein kinase, ZIP-kinase, ZIPK

Background: Serine/threonine kinase which acts as a positive regulator of apoptosis. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. Regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. Involved in the formation of promyelocytic leukemia protein nuclear body (PML-NB), one of many subnuclear domains in the eukaryotic cell nucleus, and which is involved in oncogenesis and viral infection.

Gen-ID: 1613

UniProt: O43293