HRH3 Antikörper (AA 281-380) (Biotin)
Kurzübersicht für HRH3 Antikörper (AA 281-380) (Biotin) (ABIN5675027)
Target
Alle HRH3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 281-380
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Kreuzreaktivität
- Human, Maus, Ratte
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Homologie
- Cow,Sheep,Horse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human HRH3
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- HRH3 (Histamine Receptor H3 (HRH3))
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Andere Bezeichnung
- HRH3
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Hintergrund
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Synonyms: Histamine H3 receptor, HRH3, H3R, HH3R, G-protein coupled receptor 97, GPCR97
Background: The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization. Does not bind to cimetidine and tripolidine. Shows modest affinity for thioperamide, imetit, N-alpha-methylhistamine and R--alpha-methylhistamine. Isoform 4 is unable to bind to iodoproxyfan while isoforms 1 and 3 bind it with high affinity.
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Gen-ID
- 11255
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UniProt
- Q9Y5N1
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Pathways
- cAMP Metabolic Process, Feeding Behaviour
Target
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