HRH3 Antikörper (AA 281-380)

Produktnummer ABIN5675026

Der Kaninchen Polyklonal Anti-HRH3-Antikörper wurde für WB, ELISA, IF (p), IHC (p), IF (cc), ICC und IHC (fro) validiert. Er ist geeignet, HRH3 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für HRH3 Antikörper (AA 281-380) (ABIN5675026)

Target: HRH3 (Histamine Receptor H3 (HRH3))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRH3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-HRH3 Antikörper

Bindungsspezifität: AA 281-380

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HRH3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu HRH3

Target: HRH3 (Histamine Receptor H3 (HRH3))

Andere Bezeichnung: HRH3

Hintergrund:

Synonyms: Histamine H3 receptor, HRH3, H3R, HH3R, G-protein coupled receptor 97, GPCR97

Background: The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization. Does not bind to cimetidine and tripolidine. Shows modest affinity for thioperamide, imetit, N-alpha-methylhistamine and R--alpha-methylhistamine. Isoform 4 is unable to bind to iodoproxyfan while isoforms 1 and 3 bind it with high affinity.

Gen-ID: 11255

UniProt: Q9Y5N1

Pathways: cAMP Metabolic Process, Feeding Behaviour