Hemoglobin, beta Adult Minor Chain (HBB-B2) (Middle Region) Antikörper

Produktnummer ABIN5673951

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch in WB. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Hemoglobin, beta Adult Minor Chain (HBB-B2) (Middle Region) Antikörper (ABIN5673951)

Target: Hemoglobin, beta Adult Minor Chain (HBB-B2)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: Middle Region

Sequenz: SELHCDKLHV DPENFRLLGN AIVIVLGHHL GKDFTPAAQA AFQKVVAGVA

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse HBB-B2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Antigendetails

Target: Hemoglobin, beta Adult Minor Chain (HBB-B2)

Andere Bezeichnung: HBB-B2

Hintergrund: This gene encodes a beta polypeptide chain found in adult hemoglobin, which consists of a tetramer of two alpha chains and two beta chains, and which functions in the transport of oxygen to various peripheral tissues. This gene is one of a cluster of beta-hemoglobin genes that are distally regulated by a locus control region, and which are organized along the chromosome in the order of their developmental expression. In mouse, two major strain-specific haplotypes of the beta-globin gene cluster are found - a "single" haplotype found in C57BL/-type strains, which includes two highly similar adult beta-globin genes, beta s and beta t, and a "diffuse" haplotype found in strains such as BALB/c and 129Sv, which includes two somewhat diverse adult beta-globin genes, beta-major and beta-minor. This gene represents the beta-minor adult gene found in the "diffuse" haplotype. Primary chromosome 7 of the mouse reference genome assembly, which is derived from C57BL/6 strain mice, represents the "single" haplotype, while the "diffuse" haplotype is represented in the reference genome collection by the BALB/c strain alternate contig, NT_095534.1.

Alias Symbols: Hbb2, Hbbt2, beta2, AI036344

Protein Size: 147

Gen-ID: 15130

NCBI Accession: NM_016956, NP_058652

UniProt: P02089