TDRKH Antikörper (C-Term)

Produktnummer ABIN5673744

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TDRKH in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TDRKH Antikörper (C-Term) (ABIN5673744)

Target: TDRKH (Tudor and KH Domain Containing (TDRKH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TDRKH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TDRKH Antikörper

Bindungsspezifität: C-Term

Sequenz: DMATETDASL STLLTETKKS SGEITHTLSC LSLSEAASMS GDDNLEDDYL

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TDRKH

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TDRKH

Target: TDRKH (Tudor and KH Domain Containing (TDRKH))

Andere Bezeichnung: TDRKH

Hintergrund: Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs. May act in pi-bodies and piP-bodies by transferring piRNA precursors or intermediates to or between these granules.

Alias Symbols: TDRD2

Protein Size: 561

Gen-ID: 11022

NCBI Accession: NM_001083963, NP_001077432

UniProt: Q9Y2W6