PLSCR3 Antikörper (N-Term)

Produktnummer ABIN5673452

Der Kaninchen Polyklonal anti-PLSCR3 Antikörper (ABIN5673452) detektiert spezifisch PLSCR3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PLSCR3 Antikörper (N-Term) (ABIN5673452)

Target: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLSCR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PLSCR3 Antikörper

Bindungsspezifität: N-Term

Sequenz: PPKGYAPSPP PPYPVTPGYP EPALHPGPGQ APVPAQVPAP APGFALFPSP

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PLSCR3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PLSCR3

Target: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Andere Bezeichnung: PLSCR3

Hintergrund: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.

Protein Size: 295

Gen-ID: 57048

NCBI Accession: NM_001201576, NP_001188505

UniProt: Q9NRY6

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis