NPAT Antikörper (Middle Region)

Produktnummer ABIN5673429

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch NPAT in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für NPAT Antikörper (Middle Region) (ABIN5673429)

Target: NPAT (Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPAT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NPAT Antikörper

Bindungsspezifität: Middle Region

Sequenz: TPPEGTPVEN SHSLPPESVC SSVGDSHPES QNTDDKPSSN NSAEIDASNI

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NPAT

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NPAT

Target: NPAT (Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT))

Andere Bezeichnung: NPAT

Hintergrund: Required for progression through the G1 and S phases of the cell cycle and for S phase entry. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. Also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters.

Alias Symbols: E14, p220, E14/NPAT

Protein Size: 1427

Gen-ID: 4863

NCBI Accession: NM_002519, NP_002510

UniProt: Q14207