SNAPIN Antikörper (C-Term)

Produktnummer ABIN5672645

Der Kaninchen Polyklonal anti-SNAPIN Antikörper (ABIN5672645) detektiert spezifisch SNAPIN in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SNAPIN Antikörper (C-Term) (ABIN5672645)

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNAPIN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SNAPIN Antikörper

Bindungsspezifität: C-Term

Sequenz: LLNARRRVVL VNNILQNAQE RLRRLNHSVA KETARRRAML DSGIYPPGSP

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SNAPIN

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SNAPIN

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Andere Bezeichnung: SNAPIN

Hintergrund: The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.

Alias Symbols: BLOS7, SNAPAP, BLOC1S7

Protein Size: 136

Gen-ID: 23557

NCBI Accession: NM_012437, NP_036569

UniProt: O95295

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis