CDC14B Antikörper (N-Term)

Produktnummer ABIN5672445

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CDC14B in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CDC14B Antikörper (N-Term) (ABIN5672445)

Target: CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC14B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CDC14B Antikörper

Bindungsspezifität: N-Term

Sequenz: KRKSERRSSW AAAPPCSRRC SSTSPGVKKI RSSTQQDPRR RDPQDDVYLD

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CDC14B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CDC14B

Target: CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

Andere Bezeichnung: CDC14B

Hintergrund: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

Alias Symbols: CDC14B3, Cdc14B1, Cdc14B2, hCDC14B

Protein Size: 498

Gen-ID: 8555

NCBI Accession: NM_001077181, NP_001070649

UniProt: O60729