Cadherin 8 Antikörper (C-Term)

Produktnummer ABIN5672087

Dieser Anti-Cadherin 8 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Cadherin 8 in WB. Geeignet für Human.

Kurzübersicht für Cadherin 8 Antikörper (C-Term) (ABIN5672087)

Target: Cadherin 8 (CDH8)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Cadherin 8 Antikörper

Bindungsspezifität: C-Term

Sequenz: QIYGYEGRGS VAGSLSSLES TTSDSDQNFD YLSDWGPRFK RLGELYSVGE

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CDH8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Cadherin 8

Target: Cadherin 8 (CDH8)

Andere Bezeichnung: CDH8

Hintergrund: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.

Alias Symbols: Nbla04261

Protein Size: 799

Gen-ID: 1006

NCBI Accession: NM_001796, NP_001787

UniProt: P55286

Pathways: Cell-Cell Junction Organization