TPRKB Antikörper (N-Term)

Produktnummer ABIN5671498

Der Kaninchen Polyklonal anti-TPRKB Antikörper wird verwendet zum Nachweis von TPRKB in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für TPRKB Antikörper (N-Term) (ABIN5671498)

Target: TPRKB (TP53RK Binding Protein (TPRKB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPRKB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TPRKB Antikörper

Bindungsspezifität: N-Term

Sequenz: LTHQLDLFPE CRVTLLLFKD VKNAGDLRRK AMEGTIDGSL INPTVIVDPF

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TPRKB

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TPRKB

Target: TPRKB (TP53RK Binding Protein (TPRKB))

Andere Bezeichnung: TPRKB

Hintergrund: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t6A activity of the complex. TPRKB is not required for tRNA modification.

Alias Symbols: CGI-121

Protein Size: 214

Gen-ID: 51002

NCBI Accession: NM_016058, NP_057142