SPG21 Antikörper (N-Term)

Produktnummer ABIN5671445

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SPG21 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SPG21 Antikörper (N-Term) (ABIN5671445)

Target: SPG21 (Spastic Paraplegia 21 (SPG21))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPG21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SPG21 Antikörper

Bindungsspezifität: N-Term

Sequenz: GTVPLKKIIV DDDDSKIWSL YDAGPRSIRC PLIFLPPVSG TADVFFRQIL

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of Human SPG21

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SPG21

Target: SPG21 (Spastic Paraplegia 21 (SPG21))

Andere Bezeichnung: SPG21

Hintergrund: The protein encoded by this gene binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. Mutations in this gene are associated with autosomal recessive spastic paraplegia 21 (SPG21), also known as mast syndrome. Alternative splicing results in multiple transcript variants.

Alias Symbols: MAST, ACP33, GL010, BM-019

Protein Size: 281

Gen-ID: 51324

NCBI Accession: NM_001127889, NP_001121361