Arhgef9 Antikörper (N-Term)

Produktnummer ABIN5671437

Der Kaninchen-Polyklonal Anti-Arhgef9-Antikörper wurde für WB validiert. Er ist geeignet zum Nachweis von Arhgef9 in Proben aus Human. }

Kurzübersicht für Arhgef9 Antikörper (N-Term) (ABIN5671437)

Target: Arhgef9 (Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Arhgef9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Arhgef9 Antikörper

Bindungsspezifität: N-Term

Sequenz: DEEGWFPASF VRLWVNQEDE VEEGPSDVQN GHLDPNSDCL CLGRPLQNRD

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ARHGEF9

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Arhgef9

Target: Arhgef9 (Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9))

Andere Bezeichnung: ARHGEF9

Hintergrund: The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: PEM2, EIEE8, PEM-2, HPEM-2, COLLYBISTIN

Protein Size: 516

Gen-ID: 23229

NCBI Accession: NM_001173479, NP_001166950

UniProt: O43307

Pathways: Neurotrophin Signalübertragung