FKBP5 Antikörper (N-Term)

Produktnummer ABIN5671411

Der Kaninchen Polyklonal Anti-FKBP5 Antikörper wurde für WB validiert. Er ist geeignet, FKBP5 in Proben von Human zu detektieren.

Kurzübersicht für FKBP5 Antikörper (N-Term) (ABIN5671411)

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FKBP5 Antikörper

Bindungsspezifität: N-Term

Sequenz: SNGKKFDSSH DRNEPFVFSL GKGQVIKAWD IGVATMKKGE ICHLLCKPEY

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FKBP5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FKBP5

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Andere Bezeichnung: FKBP5

Hintergrund: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Alias Symbols: P54, AIG6, FKBP51, FKBP54, PPIase, Ptg-10

Protein Size: 457

Gen-ID: 2289

NCBI Accession: NM_001145775, NP_001139247

UniProt: Q13451