XRN2 Antikörper (C-Term)

Produktnummer ABIN5671406

Der Kaninchen Polyklonal anti-XRN2 Antikörper (ABIN5671406) detektiert spezifisch XRN2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für XRN2 Antikörper (C-Term) (ABIN5671406)

Target: XRN2 (5'-3' Exoribonuclease 2 (XRN2))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XRN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-XRN2 Antikörper

Bindungsspezifität: C-Term

Sequenz: QNAAFQPNQY QMLGGPGGYP PRRDDHRGGR QGYPREGRKY PLPPPSGRYS

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of Mouse XRN2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu XRN2

Target: XRN2 (5'-3' Exoribonuclease 2 (XRN2))

Andere Bezeichnung: XRN2

Hintergrund: Possesses 5'->3' exoribonuclease activity. May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites.

Protein Size: 951

Gen-ID: 24128

NCBI Accession: NM_011917, NP_036047

UniProt: Q9DBR1