PHOX2B Antikörper (C-Term)

Produktnummer ABIN5671377

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PHOX2B in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PHOX2B Antikörper (C-Term) (ABIN5671377)

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHOX2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PHOX2B Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: PHOX2B Antibody - C-terminal region

Sequenz: RAAAAAAAAA KNGSSGKKSD SSRDDESKEA KSTDPDSTGG PGPNPNPTPS

Produktmerkmale: This is a rabbit polyclonal antibody against PHX2B. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PHX2B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74127-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PHOX2B

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Andere Bezeichnung: PHOX2B

Hintergrund:

Background Information: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.

Gene Name: paired like homeobox 2B

Alternative Symbols: CCHS, PMX2B, NBLST2, NBPhox

Protein Name: paired mesoderm homeobox protein 2B

Molekulargewicht: 34kDa

Gen-ID: 8929

NCBI Accession: NP_003915

UniProt: Q99453