Shugoshin Antikörper (AA 1-292)

Produktnummer ABIN566873

Der Maus Monoklonal Anti-Shugoshin-Antikörper wurde für ELISA, WB und IP validiert. Er ist geeignet, Shugoshin in Proben von Human zu detektieren. Es sind 9+ Publikationen verfügbar.

Kurzübersicht für Shugoshin Antikörper (AA 1-292) (ABIN566873)

Target: Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Shugoshin Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Klon: 3C11

Produktdetails anti-Shugoshin Antikörper

Bindungsspezifität: AA 1-292

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant SGOL1.

Sequenz: MAKERCLKKS FQDSLEDIKK RMKEKRNKNL AEIGKRRSFI AAPCQIITNT STLLKNYQDN NKMLVLALEN EKSKVKEAQD IILQLRKECY YLTCQLYALK GKLTSQQTVE PAQNQEICSS GMDPNSDDSS RNLFVKDLPQ IPLEETELPG QGESFQIEAT PPETQQSPHL SLKDITNVSL YPVVKIRRLS LSPKKNKASP AVALPKRRCT ASVNYKEPTL ASKLRRGDPF TDLCFLNSPI FKQKKDLRRS KKRALEVSPA KEAIFILYYV REFVSRFPDC RKCKLETHIC LR

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: SGOL1 (AAH17867, 1 a.a. ~ 292 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-Shugoshin Antikörper (ABIN566873)

Nijenhuis, Vallardi, Teixeira, Kops, Saurin: "Negative feedback at kinetochores underlies a responsive spindle checkpoint signal." in: Nature cell biology, Vol. 16, Issue 12, pp. 1257-64, (2014) (PubMed).

Wang, Mayer, Stemmann, Nigg: "Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division." in: Journal of cell science, Vol. 123, Issue Pt 5, pp. 806-13, (2010) (PubMed).

Shouse, Nobumori, Liu: "A B56gamma mutation in lung cancer disrupts the p53-dependent tumor-suppressor function of protein phosphatase 2A." in: Oncogene, Vol. 29, Issue 27, pp. 3933-41, (2010) (PubMed).

Nozawa, Nagao, Masuda, Iwasaki, Hirota, Nozaki, Kimura, Obuse: "Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation." in: Nature cell biology, Vol. 12, Issue 7, pp. 719-27, (2010) (PubMed).

Garcia-Cruz, Brieño, Roig, Grossmann, Velilla, Pujol, Cabero, Pessarrodona, Barbero, Garcia Caldés: "Dynamics of cohesin proteins REC8, STAG3, SMC1 beta and SMC3 are consistent with a role in sister chromatid cohesion during meiosis in human oocytes." in: Human reproduction (Oxford, England), Vol. 25, Issue 9, pp. 2316-27, (2010) (PubMed).

Hayashi-Takanaka, Yamagata, Nozaki, Kimura: "Visualizing histone modifications in living cells: spatiotemporal dynamics of H3 phosphorylation during interphase." in: The Journal of cell biology, Vol. 187, Issue 6, pp. 781-90, (2009) (PubMed).

Fu, Ding, Yuan, Aikhionbare, Yao, Cai, Jiang, Yao: "Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis." in: Cell research, Vol. 17, Issue 7, pp. 608-18, (2007) (PubMed).

Thein, Kleylein-Sohn, Nigg, Gruneberg: "Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity." in: The Journal of cell biology, Vol. 178, Issue 3, pp. 345-54, (2007) (PubMed).

Dai, Sullivan, Higgins: "Regulation of mitotic chromosome cohesion by Haspin and Aurora B." in: Developmental cell, Vol. 11, Issue 5, pp. 741-50, (2006) (PubMed).

Details zu Shugoshin

Target: Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))

Andere Bezeichnung: SGOL1

Hintergrund: Full Gene Name: shugoshin-like 1 (S. pombe)
Synonyms: NY-BR-85,SGO,Sgo1

Gen-ID: 151648

Pathways: Maintenance of Protein Location