Rekombinanter CD4 Antikörper
Kurzübersicht für Rekombinanter CD4 Antikörper (ABIN5668249)
Target
Alle CD4 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-CD4 [MT310], Mouse IgG1, kappa
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Spezifität
- This antibody is specific for the CD4 extracellular domain D1 (binding the HIV-1 gp120-binding site).
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Kreuzreaktivität
- Cynomolgus, Rhesusaffen
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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Aufreinigung
- Protein A affinity purified
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Isotyp
- IgG1 kappa
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anti-CD4 (CD4) (AA 385-457) antibody
CD4 Reaktivität: Human, Maus, Ratte, Huhn, Schwein FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD4 (CD4) antibodyCD4 Reaktivität: Human, Maus, Ratte, Huhn, Affe, Hund, Schwein, Kaninchen, Cat, Rind (Kuh), Schaf, Meerschweinchen, Ziege, Pferd, Avian, Esel, Hamster WB, IHC Wirt: Ziege Polyclonal unconjugated
anti-CD4 (CD4) (AA 231-330) antibodyCD4 Reaktivität: Human, Maus, Ratte FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD4 (CD4) (N-Term) antibodyCD4 Reaktivität: Human FACS, WB, MS Wirt: Maus Monoclonal MEM-241 unconjugated
anti-CD4 (CD4) antibodyCD4 Reaktivität: Human, Maus, Ratte IF, IHC (p) Wirt: Maus Monoclonal unconjugated
anti-CD4 (CD4) antibodyCD4 Reaktivität: Maus FACS, IP, IHC (fro), ICC, Func Wirt: Ratte Monoclonal GK1-5 unconjugated
anti-CD4 (CD4) (AA 26-200) antibodyCD4 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD4 (CD4) (N-Term) antibody (FITC)CD4 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-241 FITC
anti-CD4 (CD4) (AA 301-400) antibodyCD4 Reaktivität: Human, Maus, Ratte FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD4 (CD4) (N-Term) antibody (PE)CD4 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-241 PE
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Applikationshinweise
- This antibody strongly inhibits HIV-1 gp120-binding to CD4, which blocks HIV infectivity of CD4+ T lymphocytes, as well as the binding of MHCII, which results in the block of T-cell activation (possibly leading to anergy induction) (Qin et al., 2001, PMID: n/a). Additionally, antibody binding to CD4 leads to GM-CSF, TNF-α and IL-10 induction. (TNF-α induction only occurs after 20 hours.)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD4
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Andere Bezeichnung
- CD4
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Hintergrund
- Leu3/T3, T-cell differentiation antigen, Ly-4, L3T4, T-cell surface antigen T4/Leu-3
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UniProt
- P01730
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Pathways
- T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events
Target
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